Human Amniotic Membrane (HAM) in Oral and Maxillofacial Surgery: A Comprehensive Review
Keywords:HAM, Human amniotic membrane, arthroplasty
The amniotic membrane or amnion is the innermost layer of the placenta, which consist of a thick basement membrane and an avascular stromal matrix. It’s a metabolically active membrane which involved in solute and water maintaining amniotic fluid homeostasis. It has various properties such as Anti-inflammatory, Anti-microbial, Anti- fibrotic, Anti- apoptotic, Immunomodulatory, Epitheliazation & cell differentiation –modulating capacity, Inhibition of cancer cell proliferation, Low immunogenicity, Reasonable mechanical property, etc its uses has been described in the literature for various applications in the fields of ophthalmology, plastic surgery and in Oral and Maxillofacial Surgery. In this review we are listing the various applications of Human Amniotic Membrane (HAM) in the field of oral and maxillofacial surgery which are available in the literature. The various applications of HAM are i)Repair of oroantral fistula ii) after Vestibuloplasty as a bandage, iii)Maxillofacial soft tissue defects,iv)Cervical necrotising fasciitis v)BRONJ vi) treatment of Gingival recession vii) Socket preservation after extraction and viii) after ankylosis surgery of TMJ and using as an Interpositionalmaterial etc. In this review we are focussing on various applications
of HAM in OMFS.