Photodynamic Therapy – Coupling Of Light And Dye – A Review

Authors

  • Dr. V.R. Balaji, Dr. M. Allan Jeba Seeli, Dr. D. Manikandan CSI College of Dental Sciences and Research, Madurai.

Keywords:

Antimicrobial Therapy, Bacterial Resistance, Periodontal Disease, Photodynamic Therapy, Photosensitizers.

Abstract

The oral cavity is colonized by a large number and highly diversified communities of micro-organisms. Bacterial biofilm present on tooth or root surface is a major cause of gingivitis and periodontitis. Chemical antimicrobial agents are widely used in prophylactic and therapeutic regimens for dental plaque related diseases. As these agents are difficult to maintain at therapeutic concentrations in the oral cavity and can be rendered ineffective by resistance development in target organisms, there is a need for an alternative antimicrobial approach. A novel approach, photodynamic therapy (PDT), could be a solution to these problems. Lethal photosensitization of many bacteria, both Gram positive and Gram negative was found in many studies. The advantage of this new approach includes rapid bacterial elimination, minimal chance of resistance development and safety of adjacent host tissue and normal microflora.

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Published

2021-07-28

How to Cite

Dr. V.R. Balaji, Dr. M. Allan Jeba Seeli, Dr. D. Manikandan. (2021). Photodynamic Therapy – Coupling Of Light And Dye – A Review. World Journal of Advanced Scientific Research, 4(4), 48-59. Retrieved from http://wjasr.in/index.php/wjasr/article/view/225